Pollinator Medicinal

Chinese Quinine

Dichroa febrifuga

$23.00 Sold out
1 Gallon USDA Zones 8–11 Full Sun and Part Shade Matures 3–6 Feet

Dichroa febrifuga, the blue evergreen hydrangea relative, carries lacecap blue flowers and iridescent metallic-blue berries, and is famed in China as the antimalarial herb chang shan.

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Few garden shrubs carry a resume like Dichroa febrifuga. In the ground this is a handsome, medium evergreen with lacecap heads of small blue flowers in late spring and, better still, clusters of berries in fall that ripen to an almost unreal iridescent, metallic blue, the kind of structural color usually reserved for beetles and tropical birds. A relatively recent introduction from China, the plant sits close enough to Hydrangea, in the family Hydrangeaceae, that the same trick applies: acidic soil deepens the flowers and fruit to true blue, while alkaline ground pushes them toward pink.

Both halves of the botanical name reward a moment of attention. Dichroa comes from the Greek for two-colored, a nod to those shifting blues and pinks, while the epithet febrifuga is plain Latin for fever-dispelling, and that second word opens onto two thousand years of history. In China the plant is chang shan, named for Mount Chang, and ranks among the fifty fundamental herbs of traditional medicine. The roots appear in the Shennong Bencao Jing, the oldest surviving Chinese materia medica, and again in Zhang Zhongjing's Han-dynasty Treatise on Cold Damage, prescribed above all against the recurring fevers of malaria.

The modern chapter is just as remarkable. In the twentieth century, chemists chasing the herb's power isolated the alkaloids febrifugine and isofebrifugine, and those molecules in turn inspired a synthetic derivative, halofuginone, that has since traveled far from the fever clinic, serving as an anticoccidial in poultry feed and as a research compound studied for fibrosis, cancer, and autoimmune disease. The tradition came with a hard catch that modern study confirmed, since chang shan is strongly emetic and toxic to the liver in more than small amounts, which is exactly why the plant belongs in the garden as an ornamental while the pharmacology belongs in the laboratory. Nothing here is medical advice.

Set against that heritage, the garden role is refreshingly simple. Grow Dichroa febrifuga as a lush, shade-loving shrub for a woodland border, a shaded courtyard, or a mixed planting where the metallic fall berries can be admired at close range, and keep the soil acidic for the deepest blue. The plant is handsome with hydrangeas, ferns, hostas, and aucuba, takes happily to a large container that can shelter under cover at the cold edge of the range, and asks only for moist, well-drained soil in morning sun or dappled shade.

Photo courtesy of Cambridge Botanic Garden.

Will this plant thrive in your zone?

Explore this plant’s medicinal profile
Plant Profile
At a glance
Hardiness
USDA Zones 8–11
Sun
Full Sun, Part Shade
Soil
Well-drained, Fertile
Mature size
Height 3–6 Feet · Spread 3–4 Feet
Growth rate
Moderate
Seasonality
Evergreen
Design Notes

Grow Dichroa as a lush, shade-loving shrub for a woodland border, a courtyard, or a mixed shade planting, prized as much for the metallic blue berries as the hydrangea-like bloom. Site where the fall fruit can be seen up close.

Acidic soil deepens the blue of both flower and berry. Handsome with hydrangeas, ferns, hostas, and aucuba, and easily container-grown to overwinter under cover at the cold edge of the range.

Flower, Fruit & Foliage

Small, blue, flat topped clusters, spring

Flower. Small, star-shaped flowers in flat-topped clusters, blue on acidic soil and pinker on alkaline, opening from late spring into summer.

Fruit. The real show: rounded, iridescent metallic-blue berries in fall, holding well against the foliage.

Foliage. Glossy, deep green, pointed leaves, evergreen in mild climates.

Care

Read our full care guide

Light. Partial shade to full sun, best with morning sun and afternoon shade in hot climates.

Soil. Moist, fertile, well-drained soil. Acidic ground gives the truest blue in flower and fruit.

Water. Water regularly and keep evenly moist. Mulch to hold moisture and steady the roots.

Pruning. Prune lightly after flowering to shape. Avoid hard pruning, which costs the next display.

Hardiness. USDA zones 8 to 11. In colder areas, grow in a container and shelter over winter.

Medicinal & Traditional Use
Traditional profile
Tradition
Chinese
Parts used
Root, Leaves
Preparation
Decoction
Active compounds
Febrifugine, Isofebrifugine, Quinazolinone alkaloids
Research evidence
3 / 5
Traditional uses
Immune SupportDigestive Health
History & tradition

Known in China as chang shan, Dichroa febrifuga counts among the fifty fundamental herbs of traditional Chinese medicine, with a record of use against fevers and malaria stretching back more than two thousand years. The roots and leaves were decocted for intermittent fevers, and in the twentieth century chemists isolated the active alkaloids febrifugine and isofebrifugine, which in turn inspired the modern derivative halofuginone.

That research also revealed the catch behind the tradition: the herb is strongly emetic and toxic to the liver in more than small amounts. This account is shared as cultural and botanical history and is not medical advice.

References & research
Please note

These statements have not been evaluated by the Food and Drug Administration. This information is shared for traditional and educational interest only and is not intended to diagnose, treat, cure, or prevent any disease. Please consult a qualified healthcare professional before any medicinal use.

  • Strongly emetic and nauseating
  • Toxic in overdose, with liver and gastrointestinal effects
  • Traditional antimalarial use is not a substitute for modern treatment
  • Not safe for self-administration
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From rooting to shipping, our top priority is ensuring you receive healthy, thriving plants for your garden’s success.

Woodlanders Growing Process

Because most of our plants are grown from rooted cuttings — alongside seed, air layering, and grafting chosen for each variety — you receive a stronger, true-to-type plant that establishes quickly in your garden.

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Grown in Aiken, South Carolina
At Woodlanders, we are committed to quality.

All our plant material is carefully propagated, grown, and nurtured at our humble nursery in Aiken, South Carolina.

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Each plant is carefully packaged with its roots enclosed in a secure plastic bag containing moist soil, forming a compact root ball. To ensure safe transport, the box is padded with recycled newspaper, providing both stability and eco-friendly protection from weather during shipping.

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